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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ABCA6
All Species:
18.18
Human Site:
Y135
Identified Species:
40
UniProt:
Q8N139
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N139
NP_525023.2
1617
184286
Y135
I
F
N
E
T
F
S
Y
K
L
I
F
F
Q
G
Chimpanzee
Pan troglodytes
XP_001146278
1564
178469
L125
W
N
R
G
F
V
A
L
Q
T
A
I
N
T
A
Rhesus Macaque
Macaca mulatta
XP_001083010
1618
184304
Y135
I
F
N
E
T
F
S
Y
K
L
T
F
F
Q
G
Dog
Lupus familis
XP_850922
1621
183954
K135
F
H
D
T
F
S
Y
K
L
K
F
L
Q
G
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8K441
1624
183252
Y135
I
F
N
D
S
F
S
Y
Q
L
K
V
L
R
M
Rat
Rattus norvegicus
Q8CF82
1642
185792
Y137
V
F
K
D
V
M
S
Y
E
L
R
F
F
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509469
1722
195635
Y217
V
F
K
D
S
M
S
Y
E
L
R
F
F
P
D
Chicken
Gallus gallus
XP_415691
1546
175373
Y126
C
Y
N
Y
S
G
Q
Y
C
E
S
P
K
Y
W
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001092716
1654
185619
S134
V
V
F
L
D
S
M
S
Y
R
L
R
F
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34358
1704
191394
Y172
V
T
N
K
K
L
N
Y
R
I
L
L
G
K
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q84M24
1882
209045
W171
S
I
R
L
N
H
T
W
A
F
A
G
F
P
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.4
94.8
74.9
N.A.
67.3
40.7
N.A.
39.2
44
N.A.
40.5
N.A.
N.A.
N.A.
22.7
N.A.
Protein Similarity:
100
96.2
96.9
84.5
N.A.
80.7
61
N.A.
59.2
62.4
N.A.
61
N.A.
N.A.
N.A.
43.5
N.A.
P-Site Identity:
100
0
93.3
0
N.A.
46.6
40
N.A.
40
13.3
N.A.
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
13.3
93.3
6.6
N.A.
73.3
60
N.A.
66.6
26.6
N.A.
20
N.A.
N.A.
N.A.
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
24.8
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
44.6
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
10
0
19
0
0
0
10
% A
% Cys:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
10
28
10
0
0
0
0
0
0
0
0
0
19
% D
% Glu:
0
0
0
19
0
0
0
0
19
10
0
0
0
0
0
% E
% Phe:
10
46
10
0
19
28
0
0
0
10
10
37
55
0
0
% F
% Gly:
0
0
0
10
0
10
0
0
0
0
0
10
10
10
19
% G
% His:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
28
10
0
0
0
0
0
0
0
10
10
10
0
0
0
% I
% Lys:
0
0
19
10
10
0
0
10
19
10
10
0
10
10
0
% K
% Leu:
0
0
0
19
0
10
0
10
10
46
19
19
10
0
0
% L
% Met:
0
0
0
0
0
19
10
0
0
0
0
0
0
0
10
% M
% Asn:
0
10
46
0
10
0
10
0
0
0
0
0
10
0
10
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
10
0
37
0
% P
% Gln:
0
0
0
0
0
0
10
0
19
0
0
0
10
19
0
% Q
% Arg:
0
0
19
0
0
0
0
0
10
10
19
10
0
10
0
% R
% Ser:
10
0
0
0
28
19
46
10
0
0
10
0
0
0
0
% S
% Thr:
0
10
0
10
19
0
10
0
0
10
10
0
0
10
10
% T
% Val:
37
10
0
0
10
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% W
% Tyr:
0
10
0
10
0
0
10
64
10
0
0
0
0
10
19
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _